Metabolic consequences of antiepileptic drugs
نویسندگان
چکیده
منابع مشابه
Metabolic consequences of antiepileptic drugs.
PURPOSE OF REVIEW Chemical properties of the widely used older generation antiepileptic drugs (AEDs) suggest that they might be responsible for a number of medical comorbidities. RECENT FINDINGS AEDs which induce the cytochrome P450 system adversely affect bone, lipid, and gonadal steroid metabolism. Specifically, phenytoin causes loss of bone mass in women, and both phenytoin and carbamazepi...
متن کاملAntiepileptic Drugs
Antiepileptics are a very important class of medications, and the number of these drugs available for clinical use has increased dramatically in the last decade. The pharmacology and indications for use in a variety of physiatric patient groups are comprehensively and systematically reviewed.
متن کاملAntiepileptic Drugs
GENERIC NAME PAGE Carbamazepine 378 Clobazam 381 Clonazepam 380 Clorazepate 381 Diazepam 383 Ethosuximide 381 Ethotoin 378 Felbamate 382 Fosphenytoin 383 Gabapentin 382 Levetiracetam 382 Lamotrigine 379 Lorazepam 380 GENERIC NAME PAGE Mephenytoin 378 Mephobarbital 381 Metharbital 381 Nitrazepam 381 Oxcarbazepine 379 Phenobarbital 381 Phenytoin 377 Primidone 381 Tiagabine 381 Topiramate 379 Valp...
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Objective Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is to examine teratogenic effects of AED and the correlation between these malformations and AED in single or multiple pregnancies. Methods This is a retrospective study of malformations in child...
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Mothers exposed to Antiepileptic drugs (AEDs) are at high risk to born babies with orofacial malformations such as cleft lips. About 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. Maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. Researches show that new AEDs have less side effects than the...
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ژورنال
عنوان ژورنال: Current Opinion in Neurology
سال: 2010
ISSN: 1350-7540
DOI: 10.1097/wco.0b013e32833735e7